Comedy club · St. Louis, Missouri

Helium Comedy Club St. Louis, MO: Shows and Open Mic

1151 St Louis Galleria Street, St Louis, MO 63117 (St. Louis Galleria)

The short answer

Helium Comedy Club St. Louis is a comedy club in St. Louis, Missouri, at 1151 St Louis Galleria Street. Shows run Wednesday to Sunday most weeks, plus some Tuesdays; tickets $31–$50, 18 and over, two-item minimum. For comics, it runs an open mic (select Wednesdays when the schedule allows), and publishes no other route to the stage — ask in person.

On stage soon

Lineups belong to the club and the comedians, and can change; the listing has the last word. More shows in Missouri on the Comedy Calendar →

For comics

Open micSelect Wednesdays when the schedule allows — see the club's calendar — Sign up online with the form on the club's Open Mic page and check the posted lineup; if you are not on it, sign up in person by 6:00 PM on the night — open spots are drawn at random. Prepare at least three minutes source ↗
Getting bookedThe club publishes no submission route; ask in person.
ShowsWednesday to Sunday most weeks, plus some Tuesdays — Friday at 7:00 and 9:15 PM, Saturday at 7:00 and 9:30 PM, weeknights and most Sundays at 7:00 or 7:30 PM source ↗
RoomShowroom capacity 275 source ↗

Per the club's own site, read 29 September 2026.

What the room asks of comics
On stage
  • Prepare at least three minutes of material source ↗
Its other 6 rules
Open mic and new talent
  • The open mic runs on select nights when the schedule allows, for new and experienced comics; the calendar has the dates source ↗
  • The FAQ says the open mic is on Wednesday nights when the schedule allows (the Open Mic page says only 'select nights', and its last lineup was a Thursday) source ↗
  • Sign up online, then check the lineup posted on the Open Mic page before the night to see if you are on it source ↗
  • If you are not on the online list, sign up in person by 6:00 PM on the night; open spots are drawn at random source ↗
House rules
  • Comics must follow all safety protocols or be taken off the lineup source ↗
  • The club runs the Funniest Person in the Midwest competition, now combined with Indianapolis, for a $3,500 prize; the 2026 contest began in the summer source ↗

From the club's own pages, read 29 September 2026 — hover a rule for its exact words, or open its source. Where two of its pages disagree, both are here.

More stage time: Stage Time has open mics by night, and the Gig Board has calls for comics posted by the rooms themselves.

For fans

TicketsAbout $31 to $50 a ticket with fees included (before tax) on the comedy shows checked: general admission $31–$40, reserved $41–$50 source ↗
Age18 and over source ↗
MinimumTwo-item minimum per person in the showroom, food or drink; bar and lounge purchases do not count; an 18 percent administrative fee is added to food and drink source ↗
PhonesPhotos before or after the show only; no photos or video during the show; some shows ask you to put your phone away source ↗
ParkingLimited parking outside the club; more on the east side of the building near Dillard's and in the parking garage source ↗

As the club's own pages give them, read 30 September 2026 — tap or hover a source for its exact words.

Club Etiquette: how to be the table the room loves →

Plan the night

The night planner builds an evening around Helium Comedy Club St. Louis: where to eat before, the trip there and home, and what the night costs.

Plan a night here → The club's site ↗

Seen running on its own site, 29 September 2026.

Near Helium Comedy Club St. Louis

Comedy clubs in Missouri → · The Club Directory, coast to coast →

The Club Directory is also in the back of the D.O.C. book, Stand-Up Comedy: From Writing to Touring — $29, over 1,000 pages.

Updated 2 October 2026 · the club's facts from its own site, read 29 September 2026; its rules for comics read 29 September 2026; fans' facts read 30 September 2026